刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity. % n- B- y* \# W
1 Metastatic Colorectal Cancer (mCRC) ( a7 c% K: Q3 g
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
$ I \0 F! k5 c7 yintravenous 5-FU-based chemotherapy.
4 z! _+ I7 \' w, E) C R N• Administer 5 mg/kg when used in combination with bolus-IFL.
2 J+ d) v6 k, [1 j6 a• Administer 10 mg/kg when used in combination with FOLFOX4. 0 n& k7 ]' g9 w: R* j0 J8 x+ N
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
( X+ u. f4 w! b( V$ ?; E3 X: f The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and
$ f, `9 P! x+ \ e/ B8 dpaclitaxel. & X3 V% M5 V8 U7 K# f: t& G
3 Metastatic Breast Cancer (MBC) 3 o1 z& Z" K+ r( v
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
6 }$ n# z; l. U2 R4 Glioblastoma
0 N# E7 N3 \/ C2 O3 a: z9 K The recommended dose is 10 mg/kg every 2 weeks. # b z- @* c& ~. n/ g
5 Metastatic Renal Cell Carcinoma (mRCC)6 v/ B- D& W( P) A' K! f
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
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按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。" l; @# K& C2 R2 ?% R) [7 F O
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |